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Kyrle’s disease. Case report in a peritoneal dialysis service
Kyrle’s disease. Case report in a peritoneal dialysis service
Socorro Méndez-Balcázar 1 
, Silvia Romo-Jiménez 2, Jair R. Flores-Ruiz 3 , Simona Cram-González 4, Imix Lozada-Méndez 5 , Juan A. Gómez-Méndez 6
1 Unidad de Diálisis, Hospital General General José María Morelos y Pavón, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Ciudad de México, México; 2 Servicio de Patología, Hospital General General José María Morelos y Pavón, ISSSTE, Ciudad de México, México; 3 Servicio de Medicina Interna, Hospital General General José María Morelos y Pavón, ISSSTE, Ciudad de México, México; 4 Servicio de Medicina Interna, Centro Médico Nacional 20 de Noviembre, ISSSTE, Ciudad de México, México; 5 Facultad de Medicina, Estudios Superiores Zaragoza, Ciudad de México, México; 6 Servicio de Cirugía General, Hospital Ignacio Zaragoza, ISSSTE, Ciudad de México, México
*Correspondence: Socorro Méndez-Balcázar. Email: socomenbal@gmail.com
Abstract
Kyrle’s disease belongs to a group of perforating dermatoses. Its etiology is not well-defined, but it has been associated with chronic conditions such as type 2 diabetes, chronic liver disease, and, primarily, chronic kidney disease requiring renal replacement therapy. Clinically, it manifests in a polymorphic manner, ranging from keratotic papules to brown plaques with a central keratotic plug, and even crateriform lesions. It frequently appears on the lower extremities with an ascending distribution. We present the case of a 64-year-old woman with a history of type 2 diabetes, systemic hypertension, and chronic kidney disease treated with peritoneal dialysis, with histopathological diagnosis of Kyrle’s disease.
Keywords: Kyrle’s disease. Acquired perforating dermatosis.
